Which ADME term corresponds to the overall movement of a drug through the body, including distribution to tissues?

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Multiple Choice

Which ADME term corresponds to the overall movement of a drug through the body, including distribution to tissues?

Movement of a drug through the body, including its spread into tissues, is described by distribution. After a drug enters systemic circulation, distribution accounts for how it moves from blood to various tissues and organs, influenced by factors like blood flow, tissue permeability, lipophilicity, and protein binding. Absorption is about entry into the bloodstream from the administration site, metabolism is the chemical alteration by enzymes (mostly in the liver), and excretion is the elimination of drug or metabolites. So, the description of the overall movement through the body, including distribution to tissues, best matches distribution.

Movement of a drug through the body, including its spread into tissues, is described by distribution. After a drug enters systemic circulation, distribution accounts for how it moves from blood to various tissues and organs, influenced by factors like blood flow, tissue permeability, lipophilicity, and protein binding. Absorption is about entry into the bloodstream from the administration site, metabolism is the chemical alteration by enzymes (mostly in the liver), and excretion is the elimination of drug or metabolites. So, the description of the overall movement through the body, including distribution to tissues, best matches distribution.

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