Which ADME process removes a drug and its metabolites from the body?

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Multiple Choice

Which ADME process removes a drug and its metabolites from the body?

Excretion is the process by which a drug and its metabolites are removed from the body. This elimination occurs through routes such as the kidneys (urine), liver/biliary system (feces), and, for volatile compounds, the lungs, with other minor routes like sweat or tears also possible. This step represents the final phase of the ADME sequence, ensuring the compound and any biotransformation products are cleared after absorption, distribution, and metabolism. Absorption brings the drug into circulation, distribution spreads it through tissues, and metabolism chemically transforms it to more water-soluble forms, but excretion is what ultimately eliminates them from the body.

Excretion is the process by which a drug and its metabolites are removed from the body. This elimination occurs through routes such as the kidneys (urine), liver/biliary system (feces), and, for volatile compounds, the lungs, with other minor routes like sweat or tears also possible. This step represents the final phase of the ADME sequence, ensuring the compound and any biotransformation products are cleared after absorption, distribution, and metabolism. Absorption brings the drug into circulation, distribution spreads it through tissues, and metabolism chemically transforms it to more water-soluble forms, but excretion is what ultimately eliminates them from the body.

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